BMI1 Polyclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bs-51084R |
| Product Name | BMI1 Polyclonal Antibody |
| Applications |
ELISA
|
| Reactivity | Mouse |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Polyclonal antibody raised in rabbit against mouse BMI1 using two KLH-conjugated synthetic peptides containing a sequence from the central and the C-terminal region of the protein, respectively |
| Clonality | Polyclonal |
| Isotype | Not determined |
| Concentration | Not Determined |
| Purification | Whole antiserum from rabbit containing 0.05% azide |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C for 12 months. |
| Target | |
| Gene ID | 648 |
| Swiss Prot | P35226 |
| Synonyms | PCGF4, RNF51, FLVI2 |
| Background | Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2. |
| Application Dilution | |
| ELISA | 1:500-1000 |