| Overview |
| bs-5289R-APC-Cy7 |
| DOK1(Tyr362) Polyclonal Antibody, APC-Cy7 Conjugated |
| WB, FCM |
| Human |
| Mouse, Rat, Dog, Cow, Pig |
| Specifications |
| APC-Cy7 |
| Rabbit |
| KLH conjugated synthetic phosphopeptide derived from human DOK1 around the phosphorylation site of Tyr362 |
| Tyr362 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 1796 |
| Cytoplasm |
| DOK1 phospho Y362; DOK1 phospho Tyr362; p-DOK1 phospho Y362; docking protein 1 downstream of tyrosine kinase 1; Docking protein 1 p62dok Downstream of tyrosine kinase 1 pp62.; docking protein 1 62kD downstream of tyrosine kinase 1; Docking protein 1 62kD; Docking protein 1 62kD; Docking protein 1; DOK 1; DOK1; DOK-1; DOK1_HUMAN; Downstream of tyrosine kinase 1; p62dok; P62DOK; pp62; pp62. |
| Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling. |
| Application Dilution |
| WB |
1:300-5000 |
| FCM |
1:20-100 |
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