| Overview |
| bs-55017R |
| BAK1 Polyclonal Antibody |
| WB, IHC |
| Human, Rat |
| Specifications |
| Unconjugated |
| Rabbit |
| A synthetic peptide of human BAK1 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| 578 |
| Q16611 |
| Cytoplasm, Cell membrane |
| BAK1;BAK;BAK-LIKE;BCL2L7 |
| The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. |
| Application Dilution |
| WB |
1:300-5000 |
| IHC |
|
Powered by Bioz