Overview |
bs-6234R-Biotin |
DOK3 Polyclonal Antibody, Biotin Conjugated |
WB, IHC-P, IHC-F |
Mouse |
Human, Rat, Cow |
Specifications |
Biotin |
Rabbit |
KLH conjugated synthetic peptide derived from human DOK3 |
45-145/496 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Target |
79930 |
Cytoplasm, Cell membrane |
Docking protein 3; DOK 3; DOK Like Protein; DOKL Pending; Downstream of tyrosine kinase 3; p62 DOK Like Protein; DOK3_HUMAN. |
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate Abl functionDOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate Abl function. There are 4 isoforms generated by alternative splicing. |
Application Dilution |
WB |
1:300-1000 |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |