| Overview |
| bs-6266R-HRP |
| PTK6 Polyclonal Antibody, HRP Conjugated |
| WB, IHC-P, IHC-F |
| Human, Mouse |
| Rat, Cow, Sheep |
| Specifications |
| HRP |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Brk/PTK6 |
| 201-300/451 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C; for long storage, store at -80°C. Avoid multiple freeze-thaw cycles |
| Target |
| 5753 |
| Cytoplasm, Nucleus, Cell membrane |
| Breast tumor kinase; Breast tumour kinase; Protein tyrosine kinase 6; PTK6; Tyrosine protein kinase BRK; PTK6_HUMAN. |
| This protein encoded is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. Its presence in the nucleus appears to be linked to suppression of tumor progression. The encoded protein has been shown to undergo autophosphorylation. |
| Application Dilution |
| WB |
1:300-1000 |
| IHC-P |
1:200-400 |
| IHC-F |
1:100-500 |
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