ERCC6L Polyclonal Antibody, HRP Conjugated

Applications

  • IHC-P
  • IHC-F

Predicted Reactivity

  • Human
  • Mouse
  • Rat
  • Cow
  • Sheep
  • Pig
  • Horse
Overview
Catalog # bs-6380R-HRP
Product Name ERCC6L Polyclonal Antibody, HRP Conjugated
Applications IHC-P, IHC-F
Predicted Reactivity Human, Mouse, Rat, Cow, Sheep, Pig, Horse
Specifications
Conjugation HRP
Host Rabbit
Source KLH conjugated synthetic peptide derived from human ERCC6L
Immunogen Range 301-400/1250
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C; for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
Target
Gene ID 54821
Subcellular location Nucleus
Synonyms ATP dependent helicase ERCC6 like; DNA excision repair protein ERCC 6 like; ERCC 6L; ERCC6L; Excision repair cross complementing rodent repair deficiency complementation group 6 like; Excision repair protein ERCC6 like; FLJ20105; MGC131695; PICH; Plk1 interacting checkpoint helicase; SNF2/RAD54 family protein; Tumor antigen BJ HCC 15; ERC6L_HUMAN.
Background ERCC6L belongs to the SNF2 ATPase family and acts as an essential component of the spindle assembly checkpoint. It contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. It acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase. ERCC6L may also play a role in the teratogenic action of alcohol.
Application Dilution
IHC-P 1:200-400
IHC-F 1:100-500