| Overview |
| bs-70043R |
| Clavesin Antibody |
| WB, ICC |
| Specific for endogenous levels of the ~35 kDa clavesin 1/2 protein doublet. Isoform-specific knock down in cultured hippocampal neurons indicates that the lower and upper bands are clavesin 1 and 2, respectively. |
| Rat |
| Human, Mouse |
| Specifications |
| Unconjugated |
| Rabbit |
| Synthetic peptide corresponding to amino acid residues from the C-terminal region of rat Clavesin 1, conjugated to keyhole limpet hemocyanin (KLH). |
| Polyclonal |
| IgG |
| Lot Dependent |
| Affinity purification |
| PBS + 50% glycerol |
| Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C. |
| Target |
| 366311 |
| A6JFQ6 |
| 4 antibody, C6orf212 antibody, C6orf213 antibody, Clavesin 1 antibody, Clavesin 2 antibody, CRALBPL antibody, FLJ37248 antibody, MGC120572 antibody, MGC34646 antibody, OTTHUMP00000017122 antibody, Retinaldehyde binding protein 1 like 1 antibody, Retinaldehyde binding protein 1 like 2 antibody, RLBP1L1 antibody, RLBP1L2 antibody |
| Clavesin (clathrin vesicle associated Sec14 protein) is a novel neuron specific protein that has recently been identified and shown to be required for normal morphology of late endosomes and/or lysosomes as lentiviral-mediated knockdown of clavesin in hippocampal neurons causes lysosomal defects (Katoh et al., 2009). Additionally, upregulation of clavesin in human hepatocellular carcinoma has recently been demonstrated thus making it a useful marker for this disease state (Zhao et al., 2008). |
| Application Dilution |
| WB |
1:300-5000 |
| ICC |
1:100-500 |
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