DOPA Decarboxylase Antibody

Applications

Reactivity

Human
Rat
Bovine
Dog
Sheep
Rabbit
Guinea Pig

Overview
Catalog #	bs-70066r
Product Name	DOPA Decarboxylase Antibody
Applications	WB
Specificity	Specific for endogenous levels of the ~55 kDa DDC protein.
Reactivity	Human, Rat, Bovine, Dog, Sheep, Rabbit, Guinea Pig
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	Synthetic peptide from N-terminus region of human DOPA decarboxylase (DDC), conjugated to keyhole limpet hemocyanin (KLH).
Clonality	Polyclonal
Clone #	#REF!
Isotype	IgG
Concentration	Lot Dependent
Purification	Antigen Affinity purification from Pooled whole antiserum
Storage Buffer	10 mM HEPES (pH 7.5), 150 mM NaCl, 100 g per ml BSA and 50% glycerol.
Storage Condition	Storage at -20C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20C.
Target
Gene ID	1644
Swiss Prot	P20711
Synonyms	AADC antibody, Aromatic L Amino Acid Decarboxylase antibody, Aromatic-L-amino-acid decarboxylase antibody, DDC antibody, DDC_HUMAN antibody, DOPA decarboxylase (aromatic L-amino acid decarboxylase) antibody, DOPA decarboxylase antibody
Background	DOPA decarboxylase (aromatic L-amino acid decarboxylase, AADC; DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin (Waymire and Haycock, 2002; Berry et al., 1996; Haycock et al., 2003). It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinsons disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999).
Application Dilution
WB	1:300-5000