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Dopamine ß-Hydroxylase, C-Terminus Antibody

Applications

  • WB

Reactivity

  • Human
  • Mouse
  • Non-Human Primate
Overview
Catalog # bs-70067S
Product Name Dopamine ß-Hydroxylase, C-Terminus Antibody
Applications WB
Specificity Specific for endogenous levels of the ~75 kDa DBH protein.
Reactivity Human, Mouse, Non-Human Primate
Specifications
Conjugation Unconjugated
Host Sheep
Source Synthetic peptide from the C-terminal region of human dopamine β-hydroxylase (DBH), conjugated to keyhole limpet hemocyanin (KLH).
Clonality Polyclonal
Isotype IgG
Concentration Lot Dependent
Purification Antigen Affinity purification from Pooled whole antiserum
Storage Buffer 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
Storage Condition Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
Target
Gene ID 1621
Swiss Prot P09172
Synonyms dbh antibody, DBM antibody, Dopamine beta hydroxylase antibody, Dopamine beta monooxygenase antibody, Dopamine beta-hydroxylase (dopamine beta-monooxygenase) antibody, Dopamine beta-monooxygenase antibody, DOPO_HUMAN antibody, OTTHUMP00000022501 antibody, Soluble dopamine beta-hydroxylase antibody
Background DBH catalyzes the conversion of dopamine to norepinephrine and serves as a marker of noradrenergic cells. DBH antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). The expression of DBH is also elevated during stress (Sabban and Kvetnansky, 2001).
Application Dilution
WB 1:300-5000