Dopamine -Hydroxylase, N-Terminus Antibody

Applications

Reactivity

Human
Non-Human Primate

Overview
Catalog #	bs-70068s
Product Name	Dopamine -Hydroxylase, N-Terminus Antibody
Applications	WB
Specificity	Specific for endogenous levels of the ~75 kDa DBH protein.
Reactivity	Human, Non-Human Primate
Specifications
Conjugation	Unconjugated
Host	Sheep
Source	Synthetic peptide from the N-terminal region of human dopamine _-hydroxylase (DBH), conjugated to keyhole limpet hemocyanin (KLH).
Clonality	Polyclonal
Clone #	#REF!
Isotype	IgG
Concentration	Lot Dependent
Purification	Antigen Affinity purification from Pooled whole antiserum
Storage Buffer	10 mM HEPES (pH 7.5), 150 mM NaCl, 100 g per ml BSA and 50% glycerol.
Storage Condition	Storage at -20C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20C.
Target
Gene ID	1621
Swiss Prot	P09172
Synonyms	dbh antibody, DBM antibody, Dopamine beta hydroxylase antibody, Dopamine beta monooxygenase antibody, Dopamine beta-hydroxylase (dopamine beta-monooxygenase) antibody, Dopamine beta-monooxygenase antibody, DOPO_HUMAN antibody, OTTHUMP00000022501 antibody, Soluble dopamine beta-hydroxylase antibody
Background	DBH catalyzes the conversion of dopamine to norepinephrine and serves as a marker of noradrenergic cells. DBH antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinsons disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). The expression of DBH is also elevated during stress (Sabban and Kvetnansky, 2001).
Application Dilution
WB	1:300-5000