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Dynamin Antibody

Applications

  • WB

Reactivity

  • Human
  • Mouse
  • Rat

Predicted Reactivity

  • Bovine
  • Chicken
  • Non-Human Primate
Overview
Catalog # bs-70074r
Product Name Dynamin Antibody
Applications WB
Specificity Specific for endogenous levels of the ~95 kDa dynamin protein.
Reactivity Human, Mouse, Rat
Predicted Reactivity Bovine, Chicken, Non-Human Primate
Specifications
Conjugation Unconjugated
Host Rabbit
Source Synthetic peptide corresponding to amino acid residues from the N-terminal region of human dynamin, conjugated to keyhole limpet hemocyanin (KLH).
Clonality Polyclonal
Clone # #REF!
Isotype IgG
Concentration Lot Dependent
Purification Antigen Affinity purification from Pooled whole antiserum
Storage Buffer 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 g per ml BSA and 50% glycerol.
Storage Condition Storage at -20C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20C.
Target
Gene ID 1759
Swiss Prot Q05193
Synonyms B dynamin antibody, D100 antibody, DNM 1 antibody, DNM antibody, DNM1 antibody, DYN1_HUMAN antibody, Dynamin antibody, Dynamin-1 antibody, Dynamin1 antibody
Background Dynamin is a member of a group of nerve terminal proteins called dephosphins that regulate synaptic vesicle endocytosis (Cousin et al., 2001; Graham et al., 2002; Tsuboi et al., 2002). There are 3 known isoforms of Dynamin, each having several splice variants as well. Dynamin I is expressed only in neurons whereas Dynamin II is ubiquitously expressed and Dynamin III is found primarily in the testes. Dynamin 1 is phosphorylated by PKC and dephosphorylated by calcineurin.
Application Dilution
WB 1:300-5000