| Overview |
| bs-70114R |
| GABA Transporter (GAT) 2 Antibody |
| WB, IHC |
| Specific for endogenous levels of the ~82 kDa GAT-2 protein. |
| Mouse, Rat |
| Specifications |
| Unconjugated |
| Rabbit |
| Synthetic peptide corresponding to amino acid residues from the C-terminal region of rat GAT2, conjugated to keyhole limpet hemocyanin (KLH). |
| Polyclonal |
| IgG |
| Lot Dependent |
| Affinity purification |
| 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol. |
| Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C. |
| Target |
| 171163 |
| P31646 |
| GABA transport protein antibody, GAT 2 antibody, GAT-2 antibody, GAT2 antibody, GAT3 antibody, S6A13_HUMAN antibody, SLC6A13 antibody, Sodium- and chloride-dependent GABA transporter 2 antibody, Solute carrier family 6 (Neurotransmitter transporter GABA), member 13 antibody, Solute carrier family 6 member 13 antibody |
| Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl− channel associated with the GABA-A receptor (GABA-A-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-2 is found in a wide range of neuronal and non-neuronal cells including dendrites and axon terminals as well as epithelial cells and cells forming the pia and arachnoid complex (Conti et al., 1999) |
| Application Dilution |
| WB |
1:300-5000 |
| IHC |
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