| Overview |
| bs-70205R |
| Olig1 Antibody |
| WB, IP, IHC, ICC |
| Specific for endogenous levels of the ~27 kDa Olig1 protein. |
| Human, Mouse, Rat |
| Specifications |
| Unconjugated |
| Rabbit |
| Recombinant mouse Olig1. |
| Polyclonal |
| IgG |
| Lot Dependent |
| Purified by Protein A. |
| 100 mM Glycine, 200 mM Tris, pH 8.0 |
| Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year. |
| Target |
| 50914 |
| Q9JKN5 |
| Basic domain helix loop helix protein class B 6 antibody, Basic domain helix loop helix protein class B6 antibody, BHLH B6 antibody, BHLHB 6 antibody, bHLHb6 antibody, bHLHe21 antibody, Class B basic helix-loop-helix protein 6 antibody, Class E basic helix-loop-helix protein 21 antibody, Olig 1 antibody, Olig1 antibody, OLIG1_HUMAN antibody, Oligo 1 antibody, Oligo1 antibody, Oligodendrocyte lineage transcription factor 1 antibody, Oligodendrocyte specific bHLH transcription factor 1 antibody, Oligodendrocyte transcription factor 1 antibody |
| Olig genes have been identified as the earliest known markers of oligodendrocyte lineage determination to date (Zhou et al., 2000). Olig1 is a transcription factor which promotes formation and maturation of oligodendrocytes, especially within the brain. It is expressed in the ventral spinal cord as early as 9.5 dpc and by 15.5 dpc, olig1 is dispersed throughout the gray matter. In the postnatal brain, it is present preferentially in the white matter, such as corpus callosum and cerebellar medulla. Olig1 has been demonstrated as necessary in the repair of brain lesions in patients with multiple sclerosis (Arnett et al. 2004). |
| Application Dilution |
| WB |
1:300-5000 |
| IP |
1-2ug |
| IHC |
|
| ICC |
1:100-500 |
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