Tau Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bs-70279CH |
| Product Name | Tau Antibody |
| Applications | WB, IHC, ICC |
| Specificity | Specific for the ~48, 65 & 75 kDa tau isoforms. |
| Reactivity | Human, Mouse, Rat, Bovine, Pig |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Chicken |
| Source | Recombinant full length human tau expressed in and purified from E.Coli. |
| Clonality | Polyclonal |
| Isotype | IgY |
| Concentration | Lot Dependent |
| Purification | Total IgY fraction |
| Storage Buffer | PBS + 10 mM NaN3. |
| Storage Condition | Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year. |
| Target | |
| Gene ID | 4137 |
| Swiss Prot | P10636 |
| Synonyms | AI413597 antibody, AW045860 antibody, DDPAC antibody, FLJ31424 antibody, FTDP 17 antibody, G protein beta1/gamma2 subunit interacting factor 1 antibody, MAPT antibody, MAPTL antibody, MGC134287 antibody, MGC138549 antibody, MGC156663 antibody, Microtubule associated protein tau antibody, Microtubule associated protein tau isoform 4 antibody, Microtubule-associated protein tau antibody, MSTD antibody, Mtapt antibody, MTBT1 antibody, MTBT2 antibody, Neurofibrillary tangle protein antibody, Paired helical filament tau antibody, Paired helical filament-tau antibody, PHF tau antibody, PHF-tau antibody, PPND antibody, PPP1R103 antibody, Protein phosphatase 1 regulatory subunit 103 antibody, pTau antibody, RNPTAU antibody, TAU antibody, TAU_HUMAN antibody, Tauopathy and respiratory failure included antibody |
| Background | Tau is a key microtubule-associated protein that plays an important role in the formation of microtubules in axons (Binder et al. 1985). Six tau isoforms have been identified as products of a single gene produced by alternative mRNA splicing (Goedert 1990). Tau mutations have been implicated in many neurodegenerative disorders such as Alzheimer’s disease (AD), Pick’s disease and progressive supranuclear palsy. |
| Application Dilution | |
| WB | 1:300-5000 |
| IHC | |
| ICC | 1:100-500 |
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