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Tyrosine Hydroxylase Antibody

Applications

  • WB
  • IHC

Reactivity

  • Human
  • Mouse
  • Rat
  • All mammalian

Predicted Reactivity

  • Chicken
Overview
Catalog # bs-70303s
Product Name Tyrosine Hydroxylase Antibody
Applications WB, IHC
Specificity Specific for endogenous levels of the ~60 kDa tyrosine hydroxylase protein.
Reactivity Human, Mouse, Rat, All mammalian
Predicted Reactivity Chicken
Specifications
Conjugation Unconjugated
Host Sheep
Source SDS-denatured, native rat tyrosine hydroxylase purified from pheochromocytoma.
Clonality Polyclonal
Clone # #REF!
Isotype IgG
Concentration Lot Dependent
Purification Antigen Affinity purification from Pooled whole antiserum
Storage Buffer 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 g per ml BSA and 50% glycerol.
Storage Condition Storage at -20C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20C.
Target
Gene ID 25085
Swiss Prot P04177
Synonyms Dystonia 14 antibody, DYT14 antibody, DYT5b antibody, EC 1.14.16.2 antibody, OTTHUMP00000011225 antibody, OTTHUMP00000011226 antibody, ple antibody, Protein Pale antibody, TH antibody, The antibody, TY3H_HUMAN antibody, TYH antibody, Tyrosine 3 hydroxylase antibody, Tyrosine 3 monooxygenase antibody, Tyrosine 3-hydroxylase antibody, Tyrosine 3-monooxygenase antibody, Tyrosine hydroxylase antibody
Background Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine and norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinsons disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signaling (Witkovsky et al., 2000; Salvatore et al., 2001).
Application Dilution
WB 1:300-5000
IHC