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CARD17 Polyclonal Antibody, PerCP-Cy5.5 Conjugated

Applications

  • WB
  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Predicted Reactivity

  • Human
Overview
Catalog # bs-7090R-PerCP-Cy5.5
Product Name CARD17 Polyclonal Antibody, PerCP-Cy5.5 Conjugated
Applications WB, IF(IHC-P), IF(IHC-F), IF(ICC)
Predicted Reactivity Human
Specifications
Conjugation PerCP-Cy5.5
Host Rabbit
Source KLH conjugated synthetic peptide derived from human CARD17/INCA
Immunogen Range 1-100/110
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Subcellular location Cytoplasm
Synonyms CAR17_HUMAN; CARD 17; CARD17; Caspase 1 inhibitor; Caspase recruitment domain containing protein 17; Caspase recruitment domain-containing protein 17; Caspase-1 inhibitor INCA; Caspase1 inhibitor; Inhibitory caspase recruitment domain CARD protein; Inhibitory caspase recruitment domain protein.
Background Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.
Application Dilution
WB 1:300-5000
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200