| Overview |
| bs-8623R-PE |
| TESPA1 Polyclonal Antibody, PE Conjugated |
| WB |
| Human |
| Rabbit |
| Specifications |
| PE |
| Rabbit |
| KLH conjugated synthetic peptide derived from human TESPA1 |
| 231-330/521 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 9840 |
| A2RU30 |
| Cytoplasm |
| Protein TESPA1; TESPA1; Thymocyte-expressed positive selection-associated protein 1; KIAA0748; HSPC257 |
| Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development (By similarity). Plays a role in T-cell antigen receptor (TCR)-mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes. May play a role in the regulation of inositol 1,4,5-trisphosphate receptor-mediated Ca2+ release and mitochondrial Ca2+ uptake via the mitochondria-associated endoplasmic reticulum membrane (MAM) compartment. |
| Application Dilution |
| WB |
1:300-5000 |
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