| Overview |
| bs-8809R-Biotin |
| HMG4/HMGB3 Polyclonal Antibody, Biotin Conjugated |
| IHC-P |
| Mouse, Rat |
| Specifications |
| Biotin |
| Rabbit |
| KLH conjugated synthetic peptide derived from human HMG4/HMGB3:1-100/200 |
| 1-100/200 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| 3149 |
| O15347 |
| Cytoplasm, Nucleus, Chromosome |
| High mobility group (nonhistone chromosomal) protein 4; High mobility group box 3; High mobility group protein 2a; High mobility group protein 4; High mobility group protein B3; High mobility group protein HMG4; HMG 4; HMG-2a; HMG-4; HMG2A; HMGB 3; HMGB3; HMGB3_HUMAN; MGC90319; Non histone chromosomal protein; Nonhistone chromosomal protein HMG4. |
| HMGB3 belongs to the high mobility group (HMG) protein superfamily. Like HMG1 (MIM 163905) and HMG2 (MIM 163906), HMGB3 contains DNA-binding HMG box domains and is classified into the HMG box subfamily. Members of the HMG box subfamily are thought to play a fundamental role in DNA replication, nucleosome assembly and transcription (Wilke et al., 1997 [PubMed 9370291]; Nemeth et al., 2006 [PubMed 16945912]).[supplied by OMIM, Mar 2008]
Function : Binds preferentially single-stranded DNA and unwinds double stranded DNA.
Similarity : Belongs to the HMGB family.
Contains 2 HMG box DNA-binding domains. |
| Application Dilution |
| IHC-P |
1:200-400 |
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