Overview |
bs-8809R-HRP |
HMG4/HMGB3 Polyclonal Antibody, HRP Conjugated |
IHC-P |
Mouse, Rat |
Specifications |
HRP |
Rabbit |
KLH conjugated synthetic peptide derived from human HMG4/HMGB3:1-100/200 |
1-100/200 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
3149 |
O15347 |
Cytoplasm, Nucleus, Chromosome |
High mobility group (nonhistone chromosomal) protein 4; High mobility group box 3; High mobility group protein 2a; High mobility group protein 4; High mobility group protein B3; High mobility group protein HMG4; HMG 4; HMG-2a; HMG-4; HMG2A; HMGB 3; HMGB3; HMGB3_HUMAN; MGC90319; Non histone chromosomal protein; Nonhistone chromosomal protein HMG4. |
HMGB3 belongs to the high mobility group (HMG) protein superfamily. Like HMG1 (MIM 163905) and HMG2 (MIM 163906), HMGB3 contains DNA-binding HMG box domains and is classified into the HMG box subfamily. Members of the HMG box subfamily are thought to play a fundamental role in DNA replication, nucleosome assembly and transcription (Wilke et al., 1997 [PubMed 9370291]; Nemeth et al., 2006 [PubMed 16945912]).[supplied by OMIM, Mar 2008]
Function : Binds preferentially single-stranded DNA and unwinds double stranded DNA.
Similarity : Belongs to the HMGB family.
Contains 2 HMG box DNA-binding domains. |
Application Dilution |
IHC-P |
1:200-400 |