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HMG4/HMGB3 Polyclonal Antibody, HRP Conjugated

Applications

  • IHC-P

Reactivity

  • Mouse
  • Rat
Overview
Catalog # bs-8809R-HRP
Product Name HMG4/HMGB3 Polyclonal Antibody, HRP Conjugated
Applications IHC-P
Reactivity Mouse, Rat
Specifications
Conjugation HRP
Host Rabbit
Source KLH conjugated synthetic peptide derived from human HMG4/HMGB3:1-100/200
Immunogen Range 1-100/200
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 3149
Swiss Prot O15347
Subcellular location Cytoplasm, Nucleus, Chromosome
Synonyms High mobility group (nonhistone chromosomal) protein 4; High mobility group box 3; High mobility group protein 2a; High mobility group protein 4; High mobility group protein B3; High mobility group protein HMG4; HMG 4; HMG-2a; HMG-4; HMG2A; HMGB 3; HMGB3; HMGB3_HUMAN; MGC90319; Non histone chromosomal protein; Nonhistone chromosomal protein HMG4.
Background HMGB3 belongs to the high mobility group (HMG) protein superfamily. Like HMG1 (MIM 163905) and HMG2 (MIM 163906), HMGB3 contains DNA-binding HMG box domains and is classified into the HMG box subfamily. Members of the HMG box subfamily are thought to play a fundamental role in DNA replication, nucleosome assembly and transcription (Wilke et al., 1997 [PubMed 9370291]; Nemeth et al., 2006 [PubMed 16945912]).[supplied by OMIM, Mar 2008] Function : Binds preferentially single-stranded DNA and unwinds double stranded DNA. Similarity : Belongs to the HMGB family. Contains 2 HMG box DNA-binding domains.
Application Dilution
IHC-P 1:200-400