Cytochrome C Monoclonal Antibody, PerCP-Cy7 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-33193m-percp-cy7 |
| Product Name | Cytochrome C Monoclonal Antibody, PerCP-Cy7 Conjugated |
| Applications |
WB
|
| Reactivity | Human, Rat, Rabbit |
| Specifications | |
| Conjugation | PerCP-Cy7 |
| Host | Mouse |
| Source | Recombinant human Cytochrome C Protein |
| Clonality | Monoclonal |
| Clone # | 6B10 |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 54205 |
| Swiss Prot | P99999 |
| Synonyms | Cytochrome c; CYCS |
| Background | Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases. |
| Application Dilution | |
| WB | 1:300-5000 |