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Phosphotyrosine Monoclonal Antibody, Biotin Conjugated

Applications

  • IHC-P
  • IHC-F

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-33205M-Biotin
Product Name Phosphotyrosine Monoclonal Antibody, Biotin Conjugated
Applications IHC-P, IHC-F
Reactivity Human, Mouse, Rat
Specifications
Conjugation Biotin
Host Mouse
Source KLH conjugated Phosphotyrosine
Modification Site Phosphoserine
Clonality Monoclonal
Clone # 4D3
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein G.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Subcellular location Cytoplasm, Nucleus, Cell membrane
Synonyms Phospho-tyrosine; Phospho tyrosine; Phospho-tyr; Phospho tyr; p-Tyr; p-tyrosine;
Background The phosphorylation of specific tyrosine residues has been shown to be a primary mechanism of signal transduction during normal mitogenesis, cell cycle progression and oncogenic transformation, its role in other areas such as differentiation and gap junction communication, is a matter of active and ongoing research. Antibodies that specifically recognize phosphorylated tyrosine residues have proved to be invaluable to the study of tyrosine phosphorylated proteins and the biochemical pathways in which they function.
Application Dilution
IHC-P 1:200-400
IHC-F 1:100-500