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ATG5/APG5L Monoclonal Antibody, Biotin Conjugated

Applications

  • IHC-P
  • IHC-F

Reactivity

  • Rat

Predicted Reactivity

  • Human
  • Mouse
Overview
Catalog # bsm-33385M-Biotin
Product Name ATG5/APG5L Monoclonal Antibody, Biotin Conjugated
Applications IHC-P, IHC-F
Reactivity Rat
Predicted Reactivity Human, Mouse
Specifications
Conjugation Biotin
Host Mouse
Source Recombinant ATG5 Protein
Clonality Monoclonal
Clone # 5D7
Isotype IgG
Concentration 1mg/ml
Purification Purified by Protein G.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 9474
Swiss Prot Q9H1Y0
Subcellular location Cytoplasm
Synonyms ATG5; APG 5; APG 5L; APG5; APG5 autophagy 5 like; APG5 like; APG5-like; APG5L; Apoptosis specific protein; Apoptosis-specific protein; ASP; ATG 5; ATG5; ATG5 autophagy related 5 homolog; Autophagy protein 5; hAPG5; Homolog of S Cerevisiae autophagy 5; ATG5_ .
Background Required for autophagy. Conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed (By similarity).
May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.
Application Dilution
IHC-P 1:200-400
IHC-F 1:100-500