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PTPN11 (6T2) Monoclonal Antibody

Applications

  • WB

Reactivity

  • Mouse
Overview
Catalog # bsm-51075M
Product Name PTPN11 (6T2) Monoclonal Antibody
Applications WB
Reactivity Mouse
Specifications
Conjugation Unconjugated
Host Mouse
Source This PTPN11 monoclonal antibody is generated from mouse immunized with PTPN11 recombinant protein.
Clonality Monoclonal
Clone # 6T2
Isotype IgG1
Concentration 0.5ug/ul
Purification Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 5781
Swiss Prot Q06124
Synonyms CFC; NS1; JMML; SHP2; BPTP3; PTP2C; METCDS; PTP-1D; SH-PTP2; SH-PTP3; Tyrosine-protein phosphatase non-receptor type 11; Protein-tyrosine phosphatase 1D; Protein-tyrosine phosphatase 2C; PTP-2C; SHP-2; PTPN11; SHPTP2
Background Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity.
Application Dilution
WB 1:300-5000