TLE4 (4C4) Monoclonal Antibody

Applications

  • WB

Reactivity

  • Human
Overview
Catalog # bsm-51128M
Product Name TLE4 (4C4) Monoclonal Antibody
Applications WB
Reactivity Human
Specifications
Conjugation Unconjugated
Host Mouse
Source This TLE4 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the Central region of human TLE4.
Clonality Monoclonal
Clone # 4C4
Isotype IgM
Concentration 0.5ug/ul
Purification Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 7091
Swiss Prot Q04727
Synonyms ESG; BCE1; ESG4; GRG4; BCE-1; Grg-4; E(spI); Transducin-like enhancer protein 4; Groucho-related protein 4; TLE4; KIAA1261
Background Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Essential for the transcriptional repressor activity of SIX3 during retina and lens development and for SIX3 transcriptional auto-repression (By similarity).
Application Dilution
WB 1:300-5000