Overview |
bsm-51274M |
MAFK (8C5) Monoclonal Antibody |
WB, FCM |
Human |
Specifications |
Unconjugated |
Mouse |
This MAFK antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between amino acids from the human region of human MAFK. |
Monoclonal |
8C5 |
IgG1 |
0.5ug/ul |
Purified by Protein G. |
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
7975 |
O60675 |
P18; NFE2U; Transcription factor MafK; Erythroid transcription factor NF-E2 p18 subunit; MAFK |
Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |