Overview |
bsm-51305M |
IF4E (4C5) Monoclonal Antibody |
WB, IF(ICC), IF |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Mouse |
This IF4E antibody is generated from a mouse immunized with a recombinant protein of human IF4E. |
Monoclonal |
4C5 |
IgG1 |
0.5ug/ul |
Purified by Protein G. |
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
1977 |
P06730 |
CBP; EIF4F; AUTS19; EIF4E1; eIF-4E; EIF4EL1; Eukaryotic translation initiation factor 4E; eIF4E; eIF-4F 25 kDa subunit; mRNA cap-binding protein |
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap. |
Application Dilution |
WB |
1:300-5000 |
IF(ICC) |
1:50-200 |
IF |
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