DENR (2C9) Monoclonal Antibody

Applications

  • WB
  • FCM
  • IHC-P
  • IF(ICC)
  • IF

Reactivity

  • Human
Overview
Catalog # bsm-51318M
Product Name DENR (2C9) Monoclonal Antibody
Applications WB, FCM, IHC-P, IF(ICC), IF
Reactivity Human
Specifications
Conjugation Unconjugated
Host Mouse
Source This DENR antibody is generated from a mouse immunized with a recombinant protein of human DENR.
Clonality Monoclonal
Clone # 2C9
Isotype IgG2b
Concentration 0.5ug/ul
Purification Purified by Protein G.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 8562
Swiss Prot O43583
Synonyms DRP; DRP1; SMAP-3; Density-regulated protein; Protein DRP1; Smooth muscle cell-associated protein 3; DENR; H14
Background May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1.
Application Dilution
WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200
IF