Overview |
bsm-51365M |
RYK (1C1) Monoclonal Antibody |
WB, FCM |
Human |
Specifications |
Unconjugated |
Mouse |
This RYK antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 260-565 amino acids from human RYK. |
Monoclonal |
1C1 |
IgG1 |
0.5ug/ul |
Purified by Protein G. |
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
6259 |
P34925 |
JTK5; RYK1; JTK5A; D3S3195; Tyrosine-protein kinase RYK; RYK |
May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development. |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |