Overview |
bsm-52441R |
Caspase 1 (1E8) Monoclonal Antibody |
WB, FCM, IHC-P, IF(ICC) |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
C terminal Human Caspase-1 |
Monoclonal |
1E8 |
IgG |
1ug/ul |
Purified by Protein A. |
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
834 |
P29466 |
Caspase-1, Interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, p45, CASP-1, IL-1BC, ICE, IL-1 beta-converting enzyme, CASP1 |
Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |
IHC-P |
1:200-400 |
IF(ICC) |
1:50-200 |