Overview |
bsm-52777R |
Bmi1 (1C1) Monoclonal Antibody |
WB, IHC-P, IF(ICC), IHC |
Human, Rat |
Specifications |
Unconjugated |
Rabbit |
C terminal Human Bmi1 |
Monoclonal |
1C1 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Store at -20°C for 12 months. |
Target |
P35226 |
Polycomb complex protein BMI-1, Polycomb group RING finger protein 4, RING finger protein 51, BMI1 |
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2. |
Application Dilution |
WB |
1:300-5000 |
IHC-P |
1:200-400 |
IF(ICC) |
1:50-200 |
IHC |
|