Phospho-Histone H1.3(T17)+Histone H1.4(T17) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-54480R |
| Product Name | Phospho-Histone H1.3(T17)+Histone H1.4(T17) Monoclonal Antibody |
| Applications |
WB
IHC-P
IF(ICC)
IHC
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Synthetic phospho-Peptide corresponding to residues surrounding Thr17 of human H1.4. |
| Modification Site | Thr17 |
| Clonality | Monoclonal |
| Clone # | 5H3 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 3008 |
| Swiss Prot | P10412 |
| Subcellular location | Nucleus, Chromosome |
| Synonyms | Histone H1.3, Histone H1c, Histone H1s-2, HIST1H1DH1F3, Histone H1.4, Histone H1b, Histone H1s-4, HIST1H1EH1F4 |
| Background | Histone H1b are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. |
| Application Dilution | |
| WB | 1:300-5000 |
| IHC-P | 1:200-400 |
| IF(ICC) | 1:50-200 |
| IHC | |