| Overview |
| bsm-61107r-pbs-only-100ul |
| Phospho-PP2A alpha (Ser307) Recombinant Antibody, PBS Only Conjugated |
| WB, IHC-P, IHC-F, IF(IHC-P), IP |
| Human, Mouse, Rat |
| Specifications |
| PBS Only |
| Rabbit |
| KLH conjugated synthetic peptide derived from human PP2A alpha around the phosphorylation site of S307 |
| Ser307 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| PBS (pH=7.4) |
| Store at 4°C for 12 months. |
| Target |
| 5515 |
| P67775 |
| Nucleus |
| eplication protein C; PP2A-alpha; Replication protein C; RP-C; PPP2CA; MGC786. |
| PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'. |
| Application Dilution |
| WB |
1:500-2000 |
| IHC-P |
IHC-P1:50-200 |
| IHC-F |
IHC-F1:50-200 |
| IF(IHC-P) |
IFIHC-P1:50-200 |
| IP |
IP1:20-50 |
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