| Overview |
| bsm-61218r-pbs-only-100ul |
| mGluR5 Recombinant Antibody, PBS Only Conjugated |
| FCM, IHC-P, IHC-F, IF(IHC-P), IF(ICC) |
| Mouse, Rat |
| Specifications |
| PBS Only |
| Rabbit |
| KLH conjugated synthetic peptide derived from human mGluR5 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| PBS (pH=7.4) |
| Store at 4°C for 12 months. |
| Target |
| 2915 |
| P41594 |
| Cell membrane |
| GPRC1E; GRM5; Metabotropic glutamate receptor 5 precursor; MGLUR5; MGR5. |
| G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity. |
| Application Dilution |
| FCM |
1:50-100 |
| IHC-P |
IHC-P1:50-200 |
| IHC-F |
IHC-F1:50-200 |
| IF(IHC-P) |
IFIHC-P1:50-200 |
| IF(ICC) |
IFICC1:50-200 |