| Overview |
| bsm-61241r-pbs-only-100ul |
| ERR-alpha Recombinant Antibody, PBS Only Conjugated |
| WB, FCM, IP |
| Human, Mouse, Rat |
| Specifications |
| PBS Only |
| Rabbit |
| KLH conjugated synthetic peptide derived from human ERR alpha |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| PBS (pH=7.4) |
| Store at 4°C for 12 months. |
| Target |
| 2101 |
| P11474 |
| Nucleus |
| ESRRA; ERRa; ERR1; HERR1; NR3B1; Steroid hormone receptor ERR1; ERR-alpha; ERRalpha; ESRL1; Estrogen receptor-like 1; Estrogen-related receptor alpha. |
| Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle. |
| Application Dilution |
| WB |
1:500-2000 |
| FCM |
FCM1:50-100 |
| IP |
IP1:20-50 |
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