| Overview |
| bsm-61302r-pbs-only-100ul |
| FANCD2 Recombinant Antibody, PBS Only Conjugated |
| WB, IF(ICC), IP |
| Human |
| Specifications |
| PBS Only |
| Rabbit |
| KLH conjugated synthetic peptide derived from human FANCD2 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| PBS (pH=7.4) |
| Store at 4°C for 12 months. |
| Target |
| 2177 |
| Q9BXW9 |
| Nucleus |
| FA D2; FA4; FAC D2; FACD 2; FACD; FACD2; FAD; FAD2; FANCD 2; FANCD; FANCD2; Fanconi anemia group D2 protein; FLJ23826; Protein FACD2; Type 4 Fanconi pancytopenia. |
| Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress. |
| Application Dilution |
| WB |
1:500-2000 |
| IF(ICC) |
IFICC1:50-200 |
| IP |
IP1:20-50 |
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