| Overview |
| bsm-61355r-pbs-only-100ul |
| Phospho-CBL (Ser669) Recombinant Antibody, PBS Only Conjugated |
| WB |
| Human, Mouse, Rat |
| Specifications |
| PBS Only |
| Rabbit |
| KLH conjugated synthetic peptide derived from human CBL around the phosphorylation site of S669 |
| Ser669 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| PBS (pH=7.4) |
| Store at 4°C for 12 months. |
| Target |
| 867 |
| P22681 |
| Cytoplasm, Cell membrane |
| Casitas B lineage lymphoma proto oncogene; cbl; CBL2; E3 ubiquitin protein ligase CBL; Oncogene CBL2; Proto oncogene c CBL; RING finger protein 55; RNF55; Signal transduction protein CBL. |
| Participates in signal transduction in hematopoietic cells. Adapter protein that functions as a negative regulator of many signaling pathways that start from receptors at the cell surface. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. |
| Application Dilution |
| WB |
1:500-2000 |
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