FRS2 Recombinant Antibody

$25 ug total protein per lane of various lysates (see on figure) probed with FRS2 monoclonal antibody, unconjugated (bsm-61526R) at 1:1000 dilution and 4\u00b0C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.$

25 ug total protein per lane of various lysates (see on figure) probed with FRS2 monoclonal antibody, unconjugated (bsm-61526R) at 1:1000 dilution and 4\u00b0C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.

Applications

WB
IP
Flow-Cyt

Reactivity

Human

Overview
Catalog #	bsm-61526r
Product Name	FRS2 Recombinant Antibody
Applications	WB, IP, Flow-Cyt
Reactivity	Human
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human FGFR substrate 2
Clonality	Recombinant
Isotype	IgG
Concentration	Lot dependent
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Storage Condition	Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	10818
Swiss Prot	Q8WU20
Subcellular location	Cytoplasm, Cell membrane
Synonyms	FGFR signaling adaptor SNT; FGFR substrate 2; FRS2; FRS2A; FRS2 alpha; SNT; SNT1; Suc 1.
Background	Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
Application Dilution
WB	1:300-5000
IP	1-2ug
Flow-Cyt	1ug/Test