| Overview |
| bsm-61661r-pbs-only-100ul |
| FADD Recombinant Antibody, PBS Only Conjugated |
| WB, FCM, IHC-P, IHC-F, IF(IHC-P) |
| Mouse |
| Specifications |
| PBS Only |
| Rabbit |
| KLH conjugated synthetic peptide derived from mouse Fadd |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| PBS (pH=7.4) |
| Store at 4°C for 12 months. |
| Target |
| 14082 |
| Q61160 |
| Cytoplasm |
| FADD protein; GIG3; Growth inhibiting gene 3 protein; Mediator of receptor induced toxicity; MORT1. |
| Apoptotic adapter molecule that recruits caspases CASP8 or CASP10 to the activated FAS/CD95 or TNFRSF1A/TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. Active CASP8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. |
| Application Dilution |
| WB |
1:500-2000 |
| FCM |
FCM1:50-100 |
| IHC-P |
IHC-P1:50-200 |
| IHC-F |
IHC-F1:50-200 |
| IF(IHC-P) |
IFIHC-P1:50-200 |
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