| Overview |
| bsm-61790r-pbs-only-100ul |
| Exportin 1 Recombinant Antibody, PBS Only Conjugated |
| WB, FCM, IHC-P, IHC-F, IF(IHC-P), IF(ICC) |
| Human |
| Mouse, Rat |
| Specifications |
| PBS Only |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Exportin 1 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| PBS (pH=7.4) |
| Store at 4°C for 12 months. |
| Target |
| 7514 |
| O14980 |
| Cytoplasm, Nucleus |
| CRM 1; emb; Exp1; Exportin1; XPO 1. |
| Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP). Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. |
| Application Dilution |
| WB |
1:500-2000 |
| FCM |
FCM1:50-100 |
| IHC-P |
IHC-P1:50-200 |
| IHC-F |
IHC-F1:50-200 |
| IF(IHC-P) |
IFIHC-P1:50-200 |
| IF(ICC) |
IFICC1:50-200 |
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