| Overview |
| bsm-61918r |
| Pumilio 1 Recombinant Antibody |
| WB, IHC-P, IHC-F, IP, IF, Flow-Cyt, ICC/IF |
| Human, Mouse, Rat |
| Specifications |
| Unconjugated |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Pumilio 1 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol |
| Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target |
| 9698 |
| Q14671 |
| HsPUM; PUM L1; Pum1; PUMH 1; PUMH; PUMH1; Pumilio1; PUML1. |
| Sequence-specific RNA-binding protein that acts as a post-transcriptional repressor by binding the 3'-UTR of mRNA targets. Binds to an RNA consensus sequence, the Pumilio Response Element (PRE), 5'-UGUANAUA-3', that is related to the Nanos Response Element (NRE).Mediates post-transcriptional repression of transcripts via different mechanisms: acts via direct recruitment of the CCR4-POP2-NOT deadenylase leading to translational inhibition and mRNA degradation. |
| Application Dilution |
| WB |
1:300-5000 |
| IHC-P |
FCM1:20-100 |
| IHC-F |
IHC-P1:200-400 |
| IP |
IHC-F1:100-500 |
| IF |
ICC1:50-200 |
| Flow-Cyt |
IP1-2ug |
| ICC/IF |
IF |