| Overview |
| bsm-62077r-cy7-100ul |
| SorLA Recombinant Antibody, Cy7 Conjugated |
| WB, IF |
| Human, Mouse, Rat |
| Specifications |
| Cy7 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Sortilin related receptor |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 6653 |
| Q92673 |
| Cell membrane |
| gp250; LR11; LRP9; SORL1; SorLA 1; SorLA. |
| Sorting receptor that directs several proteins to their correct location within the cell (Probable). Along with AP-1 complex, involved Golgi apparatus - endosome sorting.Sorting receptor for APP, regulating its intracellular trafficking and processing into amyloidogenic-beta peptides. Retains APP in the trans-Golgi network, hence preventing its transit through late endosomes where amyloid beta peptides Abeta40 and Abeta42 are generated. |
| Application Dilution |
| WB |
1:300-5000 |
| IF |
|
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