ZNF348/Kaiso Recombinant Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-62183r |
| Product Name | ZNF348/Kaiso Recombinant Antibody |
| Applications |
WB
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human KAISO |
| Clonality | Recombinant |
| Isotype | IgG |
| Concentration | Lot dependent |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol |
| Storage Condition | Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 10009 |
| Swiss Prot | Q86T24 |
| Subcellular location | Cytoplasm, Nucleus |
| Synonyms | Kaiso; Zbtb33; ZNF Kaiso; ZNF348. |
| Background | Transcriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS). Recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. |
| Application Dilution | |
| WB | 1:300-5000 |