| Overview |
| bsm-62213r-pbs-only-100ul |
| MBNL1 Recombinant Antibody, PBS Only Conjugated |
| FCM |
| Human, Mouse |
| Specifications |
| PBS Only |
| Rabbit |
| KLH conjugated synthetic peptide derived from human MBNL1 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| PBS (pH=7.4) |
| Store at 4°C for 12 months. |
| Target |
| 4154 |
| Q9NR56 |
| Cytoplasm, Nucleus |
| EXP; EXP35; EXP40; EXP42; MBNL; MBNL1. |
| Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. Regulates the TNNT2 exon 5 skipping through competition with U2AF2. Inhibits the formation of the spliceosome A complex on intron 4 of TNNT2 pre-mRNA. |
| Application Dilution |
| FCM |
1:50-100 |
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