| Overview |
| bsm-62326r-Cy5.5-100ul |
| DOCK2 Recombinant Antibody, Cy5.5 Conjugated |
| WB, IF |
| Human |
| Specifications |
| Cy5.5 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Dedicator of cytokinesis protein 2 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 1794 |
| Q92608 |
| Cell membrane |
| DOCK 2; IMD40. |
| Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2. |
| Application Dilution |
| WB |
1:300-5000 |
| IF |
|
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