| Overview |
| bsm-62336r-pbs-only-100ul |
| ABI2 Recombinant Antibody, PBS Only Conjugated |
| WB |
| Human, Mouse, Rat |
| Specifications |
| PBS Only |
| Rabbit |
| KLH conjugated synthetic peptide derived from human ABI2 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| PBS (pH=7.4) |
| Store at 4°C for 12 months. |
| Target |
| 10152 |
| Q9NYB9 |
| Cytoplasm |
| Abelson interactor 2; ABI2; ABI2B; Abl binding protein 3; AblBP3; ArgBP1; ARGBPIA; ArgBPIB; SSH3BP2. |
| Regulator of actin cytoskeleton dynamics underlying cell motility and adhesion. Functions as a component of the WAVE complex, which activates actin nucleating machinery Arp2/3 to drive lamellipodia formation.Acts as a regulator and substrate of nonreceptor tyrosine kinases ABL1 and ABL2 involved in processes linked to cell growth and differentiation. Positively regulates ABL1-mediated phosphorylation of ENAH, which is required for proper polymerization of nucleated actin filaments at the leading edge. |
| Application Dilution |
| WB |
1:500-2000 |
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