| Overview |
| bsm-62406r-pbs-only-100ul |
| PAG1 Recombinant Antibody, PBS Only Conjugated |
| WB, FCM, IHC-P, IHC-F, IF(IHC-P), IF(ICC), IP |
| Human, Mouse, Rat |
| Specifications |
| PBS Only |
| Rabbit |
| KLH conjugated synthetic peptide derived from human PAG1 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| PBS (pH=7.4) |
| Store at 4°C for 12 months. |
| Target |
| 55824 |
| Q9NWQ8 |
| Cell membrane |
| CBP; Csk binding protein; PAG; PAG1. |
| Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling. |
| Application Dilution |
| WB |
1:500-2000 |
| FCM |
FCM1:50-100 |
| IHC-P |
IHC-P1:100-500 |
| IHC-F |
IHC-F1:100-500 |
| IF(IHC-P) |
IFIHC-P1:100-500 |
| IF(ICC) |
IFICC1:50-200 |
| IP |
IP1:20-50 |
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