| Overview |
| bsm-62438r-pbs-only-100ul |
| RanBP3 Recombinant Antibody, PBS Only Conjugated |
| FCM, IHC-P, IHC-F, IF(IHC-P), IF(ICC), IP |
| Human, Mouse |
| Specifications |
| PBS Only |
| Rabbit |
| KLH conjugated synthetic peptide derived from human RanBP3 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| PBS (pH=7.4) |
| Store at 4°C for 12 months. |
| Target |
| 8498 |
| Q9H6Z4 |
| Cytoplasm, Nucleus |
| Ran binding protein 3; RanBP3. |
| Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. |
| Application Dilution |
| FCM |
1:50-100 |
| IHC-P |
IHC-P1:100-500 |
| IHC-F |
IHC-F1:100-500 |
| IF(IHC-P) |
IFIHC-P1:100-500 |
| IF(ICC) |
IFICC1:50-200 |
| IP |
IP1:20-50 |