| Overview |
| bsm-62467r-pbs-only-100ul |
| BRMS1 Recombinant Antibody, PBS Only Conjugated |
| IHC-P, IHC-F, IF(IHC-P), IF(ICC) |
| Human |
| Specifications |
| PBS Only |
| Rabbit |
| KLH conjugated synthetic peptide derived from human BRMS1 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| PBS (pH=7.4) |
| Store at 4°C for 12 months. |
| Target |
| 25855 |
| Q9HCU9 |
| Cytoplasm, Nucleus |
| BRMS1 |
| Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma. |
| Application Dilution |
| IHC-P |
1:100-500 |
| IHC-F |
IHC-F1:100-500 |
| IF(IHC-P) |
IFIHC-P1:100-500 |
| IF(ICC) |
IFICC1:50-200 |
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