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Park7 (DJ-1) Antibody

Applications

  • WB
  • IHC
  • ICC

Reactivity

  • Human
  • Mouse
  • Rat
  • Bovine
Overview
Catalog # bsm-70215M
Product Name Park7 (DJ-1) Antibody
Applications WB, IHC, ICC
Specificity Specific for endogenous levels of the ~21 kDa Park7 protein.
Reactivity Human, Mouse, Rat, Bovine
Specifications
Conjugation Unconjugated
Host Mouse
Source Full length recombinant human Park7 expressed in and purified from E. coli.
Clonality Monoclonal
Clone # 4H4
Isotype IgG1
Concentration Lot Dependent
Purification Purified by Protein G culture supernatant
Storage Buffer PBS + 10 mM NaN3.
Storage Condition Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
Target
Gene ID 117287
Swiss Prot O88767
Synonyms CAP1 antibody, DJ-1 antibody, DJ1 antibody, DJ1 protein antibody, Epididymis secretory sperm binding protein Li 67p antibody, FLJ27376 antibody, FLJ34360 antibody, FLJ92274 antibody, HEL S 67p antibody, Oncogene DJ1 antibody, OTTHUMP00000001348 antibody, OTTHUMP00000001349 antibody, OTTHUMP00000001350 antibody, OTTHUMP00000001351 antibody, PARK7 antibody, PARK7_HUMAN antibody, Parkinson disease (autosomal recessive, early onset) 7 antibody, Parkinson disease protein 7 antibody, Parkinson protein 7 antibody, Protein DJ-1 antibody, SP22 antibody
Background Park7, also known as DJ-1, is a member of the peptidase C56 family of proteins and is thought to function as a molecular chaperone. Mutations in park7 have been associated with autosomal recessive, early onset Parkinson’s disease (Bonifati et al., 2003). Recently, park7 has been shown to inhibit microtubule associated protein 1B aggregation thus leading to neuronal apoptosis (Wang et al., 2011).
Application Dilution
WB 1:300-5000
IHC
ICC 1:100-500