HSD11B1 Polyclonal Antibody

$This image was kindly submitted by Dragos Scarlet DVM, MSc from the University of Vienna as part of the Bioss Discovery Progarm.\\n\\nParaffin embedded horse duodenum labeled with Anti-11\u00dfHSD1 Polyclonal Antibody, Unconjugated (bs-3904R) at 1:200 followed by conjugation to the secondary antibody and DAB staining$

This image was kindly submitted by Dragos Scarlet DVM, MSc from the University of Vienna as part of the Bioss Discovery Progarm.\\n\\nParaffin embedded horse duodenum labeled with Anti-11\u00dfHSD1 Polyclonal Antibody, Unconjugated (bs-3904R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

$This image was kindly submitted by Dragos Scarlet DVM, MSc from the University of Vienna as part of the Bioss Discovery Progarm.\\n\\nParaffin embedded horse kidney labeled with Anti-11\u00dfHSD1 Polyclonal Antibody, Unconjugated (bs-3904R) at 1:200 followed by conjugation to the secondary antibody and DAB staining$

This image was kindly submitted by Dragos Scarlet DVM, MSc from the University of Vienna as part of the Bioss Discovery Progarm.\\n\\nParaffin embedded horse kidney labeled with Anti-11\u00dfHSD1 Polyclonal Antibody, Unconjugated (bs-3904R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

Applications

ELISA
IHC-P
IHC-F
IF(IHC-P)
IF(IHC-F)
IF(ICC)

Reactivity

Human
Mouse
Rat
Horse

Predicted Reactivity

Dog
Cow
Sheep
Pig
Rabbit

Overview
Catalog #	bs-3904R
Product Name	HSD11B1 Polyclonal Antibody
Applications	ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity	Human, Mouse, Rat, Horse
Predicted Reactivity	Dog, Cow, Sheep, Pig, Rabbit
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human HSD11B1
Clonality	Polyclonal
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	3290
Swiss Prot	P28845
Subcellular location	Cytoplasm, Cell membrane
Synonyms	HDL; 11-DH; HSD11; HSD11B; HSD11L; CORTRD2; SDR26C1; 11-beta-HSD1; Corticosteroid 11-beta-dehydrogenase isozyme 1; 11-beta-hydroxysteroid dehydrogenase 1; HSD11B1
Background	Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol (By similarity).
Application Dilution
ELISA	1:500-1000
IHC-P	1:200-400
IHC-F	1:100-500
IF(IHC-P)	1:50-200
IF(IHC-F)	1:50-200
IF(ICC)	1:50-200